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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TCOF1 All Species: 7.58
Human Site: S734 Identified Species: 18.52
UniProt: Q13428 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13428 NP_000347.2 1488 152104 S734 A S V P V K G S L G Q G T A P
Chimpanzee Pan troglodytes XP_527074 1411 144549 V677 T G P T V T Q V K A E K Q E D
Rhesus Macaque Macaca mulatta NP_001035041 1485 152021 S732 A S V P V K G S L G Q G T A P
Dog Lupus familis XP_851848 704 74723
Cat Felis silvestris
Mouse Mus musculus O08784 1320 134983 T586 H C K A G A V T S S A S L S S
Rat Rattus norvegicus P41777 704 73545
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510162 1294 129807 G560 G S A K K P Q G R A S T P A A
Chicken Gallus gallus NP_001012803 974 101012 K240 S S E S E E E K E T P T V K A
Frog Xenopus laevis NP_001089103 1476 154336 S729 L A K P G K L S T S A K T P P
Zebra Danio Brachydanio rerio XP_689627 1001 102013 T267 P P S K K P K T G Q F S A V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.9 85.8 23.8 N.A. 50.2 24.9 N.A. 23.7 29.8 20.8 29.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.5 88.7 33.4 N.A. 60.4 33.8 N.A. 37.5 41.5 36.9 42 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 0 N.A. 0 0 N.A. 13.3 6.6 33.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 0 N.A. 13.3 0 N.A. 13.3 20 40 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 10 10 0 10 0 0 0 20 20 0 10 30 20 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 10 0 10 10 10 0 10 0 10 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 10 0 0 20 0 20 10 10 20 0 20 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 20 20 20 30 10 10 10 0 0 20 0 10 0 % K
% Leu: 10 0 0 0 0 0 10 0 20 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 10 30 0 20 0 0 0 0 10 0 10 10 40 % P
% Gln: 0 0 0 0 0 0 20 0 0 10 20 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 10 40 10 10 0 0 0 30 10 20 10 20 0 10 10 % S
% Thr: 10 0 0 10 0 10 0 20 10 10 0 20 30 0 0 % T
% Val: 0 0 20 0 30 0 10 10 0 0 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _